Molecular Mechanisms of Human Fungal Pathogen Host Interaction
The project ImResFun shall provide state-of-the-art training in infectious disease research and medical immunology targeting the most common human fungal pathogens, the opportunistic Candida species. The key objectives of ImResFun are to understand how immune cells and infected organs respond to invasion by Candida spp, to decipher host-defense mechanisms mediating pathogen elimination, and to identify genetic networks driving the dynamics of host-pathogen interplay. ImResFun will exploit cutting-edge technologies to unravel the basic mechanisms of fungal pathogenesis and host immunity, and to improve diagnosis and identify novel biomarkers of infection.