Bioinspired chemistry - Fraunhofer IGB

Our research

Sustainable syntheses and materials

In our modern society, products of the chemical industry are a part of almost all areas of daily life and our life quality greatly depends on the sustainable availability of functional chemical synthesis products.

In line with the raw materials change, the central subject of the innovation field Bioinspired Chemistry is to enable the controlled utilization of biomolecular functionalities for the development of innovative and green fine- and specialty chemicals, biobased polymers, and functional materials, applying new synthetic pathways.

We understand bioinspiration as the application of exclusive molecular structures derived from renewable resources and their maximal functional integration in chemical products. In this way, innovations in novel synthesis spaces emerge, allowing for advantageous properties particularly due to their biogenic origin.

For this we connect and combine biobased chemistry with already established technologies for future markets, driving forward demand-meeting developments in a way that is inspired by resources, function, and the chemistry of nature. We consider bioinspired chemistry as a valuable, complementary, enhancing, and viable alternative to the established, mostly fossil based chemistry.

Our concept involves focused interdisciplinary approaches of synthetic and retrosynthetic strategies combining chemical and biological aspects und therefore give way to innovative production processes. We develop holistic solutions for diverse and complex problems. We use knowledge of areas of organic chemistry, bioorganic chemistry, biotechnology, polymer chemistry and material processing. Therefore, we can give specific and agile answers to the current challenges due to our interlocking research topics, including techno-economical requirements and practical implementation.

The aim is to expand the toolbox for sustainable synthesis by an overall view on resources, conversion methods, desired product properties, processing technology, and end-of-life scenarios of the products. The performance of the products is evaluated regarding application demands and optimized for industrial usage to achieve technology leaps towards new “green” chemicals and materials comprising new functionality. For this, our leitmotif is “easy access, technologically feasible, and highly functional due to the biobased components”.

Fields of activity and technologies

Bioinspired synthesis routes

Organic chemistry

Synthesis Development
Organic synthesis of small molecules
Building blocks for new bio-based thermoplastics and epoxy resins
Modified biopolymers
- Development of purification methods
- Optimization by means of statistical experimental design
- Scale-up of syntheses

more info

Bioorganic chemistry

Chemo-enzymatic synthesis routes
Functional proteins: proteins in material and application development

more info

Biobased polymers and materials

Biobased polymers and additives

Chemical modification of polysaccharides
Controlled degradation of lignin
Conversion of biomolecules to specialty polymers
- Polyamides from monoterpenes
Development of biobased plasticizers and nucleating agents
Additivation of polymersobased materials

more info

Plastics technology

Extrusion
- Injection molding
- Thermal forming processes
- Production and material processability
Chemical analysis
- Material characterization
- Material testing
- Testing of new developed materials

more info

Biohybrid materials

Catalytically active materials
Intelligent or switchable materials
Tailor-made solutions for the agricultural industry based on residual materials

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Laboratory for technical biopolymers ‒ LTBP

In this project, which is funded by the Bavarian Ministry of State, we cover the entire value chain of biobased materials: from the identification of suitable starting materials, through functionalization, polymerization and additivation, to recyclability and biodegradability.

This makes us a competent contact for regional and national industry and research on the subject of biogenic plastics.

Dr. Robert Scherf

Dr. Harald Strittmatter

more info

Terpene-based polyamides: Caramid-R^® and Caramid-S^®

Caramid-R^® and Caramid-S^® are examples of a new class of polyamides that are produced from monoterpenes which are a side product of the pulp and paper industry. Starting from 3-carene, new lactams are synthesized by a patented process and subsequently polymerized to Caramid-R^® and Caramid-S^®.

… for further information refer to our press release:

go to press release

Range of services

We would like to be your partner for the development of sustainable synthetic procedures for innovative chemical products. We would be happy to support you concerning the choice of suitable funding possibilities.

In detail we support you for:

Research and Development

Identification of suitable raw material for the development of new products and new materials
Identification of new applications for new biobased products
Literature and patent studies
Molecular biological and technical optimization of enzymes and enzyme reactions
Custom synthesis and contract screening
Development of procedures for the utilization of residues
Development of procedures for the integration of renewable resources and their chemical structures in industrially established processes --> synthesis of biobased alternatives for fossil based compounds
Evaluation of optimized synthetic procedures for the production of target products
Optimization of reactions by design of experiment
Scale-up of reactions (up to 4 liter reaction volume; further scale-up at Fraunhofer CBP)

Cooperation for research projects

Identification of suitable funding possibilities (national, European)
Support by the formation of a project consortium and by communication with possible partners
Support by project applications
Communications with funding authorities

Characterization

Chemical analysis and structure identification
Contract analysis

Equipment

We also offer services concerning materials and (biobased) polymers as part of the Laboratory for Technical Biopolymers (LTBP):

Selection of suitable biogenic raw- and waste products
Screening of polymerization methods
Polymerization at lab scale
Functionalization of natural biopolymers
Selection and development of biobased polymer additives
Development of composite materials with natural materials
Polymer analytics
Material characterization
Material testing
Analysis of product failures and assessment
Biocompatibility
End-of-life scenarios (in planning)
- Material cycles
- Biodegradability

equipment

We are your partner for the development of the sustainable synthesis processes and the innovative chemical products of the future. We focus on the selection of biobased resources, the development of modern conversion and production processes and particularly on the application of catalytic processes (chemo-, bio- and electro-catalysis). This includes the analytical and functional evaluation of these processes and products. Following that idea, our goal is the production of new products and materials derived from renewables, residual streams, and carbon dioxide (CO₂) in an environmentally benign manner – together with our partners. For this, we rely on our modern laboratories for biotechnology, chemistry, polymer chemistry, and our technicum for material processing including the following equipment:

Synthesis/processing

Automatized laboratory reactors
High pressure reactors
Catalyst screening station
10 L fermenter
Polymerization reactor/Hydrogenation reactor
Glovebox
Ovens
Vacuum drying oven
Press
Cutting mill
Mini-Compounder
Injection moulding
Extrusion

more info

Analytics

Chemical structure determination

400 MHz-Nuclear magnetic resonance (NMR)
FTIR-spectroscopy (transmission and ATR)

Chromatographic methods

Gas chromatography (GC)
High performance liquid chromatography (HPLC)
Size exclusion chromatography / Gel permeation chromatography (SEC/GPC)
Fast protein liquid chromatography (FPLC)

Other methods

Autotitrator
TOC Analyzer

more info

Material characterization

Thermal analysis

Differential scanning calorimetry (DSC)
Thermogravimetric analysis (TGA)
Determination of the heat deflection temperature (HDT)

Mechanical properties

Pendulum impact tester
Universal testing machine
Shore hardness (DIN ISO 7619-1)
Rheology/DMA (coming 2025)
Capillary viscometry by Ubbelohde-viscosimeter

Other methods

Microscopy
Density measurement of solids and fluids
Conditioning of specimen

more info

1. Synthesis/processing

Automatized laboratory reactors

Data collection for the development of novel synthesis, optimization of reaction protocols, establishment of robust and secure processes.

SYSTEM	SHORT DESCRIPTION
Double jacket glass reactors	0,5 L – 4 L installed Upgradable to 50 L
Temperature	-10 °C – 200 °C
Parameter control	Temperature, pH-value, stirring speed, dosing of fluids

High pressure reactors

Chemical synthesis with gas reactants and high pressure.

High pressure reactors	Short description
Parallel autoclave station	Four parallel reactors in lab scale Volume: 100 mL/reactor Pressure: up to 300 bar Temperature: up to 400 °C Material: Hastelloy C22 Stirrer: gassing Computer control and exact documentation of reaction data
Small scale autoclave	Volume: 50 mL + 100 mL, Pressure: up to 150 bar Temperature: up to 250 °C Material: stainless steel
Acidulation autoclaves	Volume: 45 mL + 125 mL Pressure: up to 120 bar Temperature: up to 250 °C Material: PTFE-inlay and stainless steel shell
Parr batch reactor	Volume: 2 L Pressure: up to 100 bar Temperature: up to 350 °C Material: stainless steel Stirrer: gassing and paddle stirring

Catalyst screening station

Parallel catalyst screening under defined conditions.

Screening-System	Short description
Heterogeneous catalyst screening station	Four parallel reactors Temperature: up to 500 °C Pressure: up to 80 bar Material: Steel Gases: CO, CO₂, H₂, N2, Ar, synthetic air, hydrocarbons Gas flow: 10 – 100 mL min^-1 Fluids: H₂O (0-2.5 g h^-1)
Three-phase reactor (fixed-bed)	Volume: D = 6 mm; H = 200 mm Pressure: up to 10 bar Temperature: up to 450 °C Material: Steel or glass Gases: NH₃, N₂, synthetic air Volume flows: liquid up to 2 mL/min ; Gases up to 100 mL/min

10 L fermenter

system	short description
BBI BIOSTAT^® C C10-3 15 L vessel (hight:diameter - 3:1)	Working volume 3 – 10 L
Pressure resistance	-1 – 3 bar
Gassing control	0,6 – 30 L min^-1 (0,04 – 2 vvm), air, N₂
Stirring	2x6 paddle Rushton-Turbine 900 W brushless Motor
Pump control	4x peristaltic pumps (max. 300 mL min^-1)
Sensors	pH, pO₂, antifoam, temperature
Monitoring and (feedback) control	Control pH (1 – 13) und pO₂ (0 – 100 %) Antifoam agent dosing Media- / substrate dosing Temperature (8 – 150°C) Stirring (10 – 1.500 rpm)

Polymerization reactor/Hydrogenation reactor

2-step mini-plant for demonstration of polycondensation under application-oriented conditions and for hydrogenation of organic compounds.

system	short description
Working volume	Two 1,5 L autoclaves with distillation uni
Monitoring and (feedback) control	Fully (feedback) controlled mini-plant with gas dosing
Temperature	Up to 350 °C
Pressure	Up to 200 bar

Glovebox

system	short description
Inert atmosphere (N₂, Ar)	Allows very air- or moisture-sensitive reactions (< 1 ppm O₂ or moisture)
Pressure	-15 – 15 mbar (negative or positive pressure)

Oven

Muffle furnace and calciners with optional inert atmosphere and control unit.

system	short description
Gases	N₂, air
Temperature	Up to 1200 °C

Vacuum drying oven

system	short description
Filling capacity	115 L
Vacuum	Up to 15 mbar
Temperature	Up to 110 °C

Press

Thermal forming under pressure by pressing.

system	short description
Surface temperature	Up to 300 °C
Pressing force	Up to 200 kN

Cutting mill

The cutting mill is used for crushing of soft to medium-hard, brittle or fibrous sample material.

SYSTEM	short description
Cutting insert	3 rotor knives with 4 steel counter knives
Sieve inserts	0.2 mm, 0.5 mm, 1.0 mm and 1.5 mm trapezoid wholes
Speed range	6000 – 22000 U/min, adjustable in steps of 1000
Time function	Timer/ stopwatch
Embrittlement of the samples	Processing of brittle sample material, for example with liquid nitrogen, is possible.
Feeding material	Size max. 15 mm
Throughput quantity	Up to 15 L/h -> Sample dependent

Mini-Compounder

Twin-screw extruder for processing very small quantities. Used to determine initial material-specific characteristics.

SYSTEM	short description
Cyclinder capacity	15 mL
Temperature	Up to 400 °C
Rotation speed	Up to 250 rpm
Torque value	Up to 40 Nm
Material properties	Cylinder (64 HRC, 2000 Vickers) and screws (56 HRC, 1000 Vickers) are wear-resistant, abrasion-resistant and chemical-resistant.
Bypass valve	Possibility of material return or continuous extrusion
Data recording via software	Graphical presentation and recording of extrusion parameters (temperature, melt viscosity, shear forces, torque). Can be saved as an Excel file.

Injection moulding

System	short description
MiniJet	Plunger plastification
Injection moulding	Screw plastification

Extrusion

Planetary roller extruder

2. Analytics

2.1. Chemical structure determination

400 MHz-Nuclear magnetic resonance (NMR)

NMR spectroscopy

Structure determination of organic molecules, end-group determination of polymers, and reaction monitoring (qualitatively and quantitatively).

system	short description
9,4 Tesla Magnet	Frequenz 400 MHz
5 mm probe head	Automatically tunable in the range from ¹H to ¹⁹F and ³¹P to ¹⁰⁹Ag, field gradient up to 140 G/cm
2 channel spectrometer	1D and 2D measurements: COSY, HMQC, HMBC, NOESY, ROESY, TOCSY, and DOSY
Variable temperature control	-100 °C – 150 °C

FTIR-spectroscopy (transmission and ATR)

Structure determination and reaction control.

system	short description
ATR unit	Non-destructive substance analysis of solids and fluids
Transmittance measurements (KBr pellets)	Quantitative analysis

2.2. Chromatographic methods

Gas chromatography (GC)

Gas chromatography is used for the qualitative and quantitative analysis of organic substances and mixtures. This requires vaporization without decomposition of each component.

GC-system	short description
Single-Quad-MS-Detector (mass spectrometry)	Identification and determination of components of mixtures such as coatings, natural substances, flavors and odorants
FID (flame ionization detector)	Robust detector for oranic compounds with high sensitivity (detection limit 1 ng)
TCS (thermal conductivity scanner)	Universal detector
Headspace	Analysis of highly volatile substances
SPME (solid phase micro extraction)	Analysis of samples with low compound concentration by adsorptio
Sample introduction options	On-column, SSL (split/splitless), PTV (programmed temperature vaporizer)

High performance liquid chromatography (HPLC)

High performance liquid chromatography is used for qualitative and quantitative analysis of organic mixtures.

HPLC-system	short description
DAD (Dioden-Array-Detector)	UV/Vis absorbance (full spectrum)
ELSD (Evaporative Light Scattering Detector)	Compound analysis by structure-specific light scattering
RID (Refractive Index Detector)	Detection by refractive index changes
MS-Detector (mass spectrometry)	Identification and quantification of compounds, MSⁿ-spectra

Size exclusion chromatography / Gel permeation chromatography (SEC/GPC)

Determination of molecular weight distribution from 10² – 10⁷ g/mol.

system	short description
GPC	Isocratic Pump, HFIP-compatible devices Pressure: 200 bar
Differential-refractometer RI-detector	Concentration detector for regular GPC by standard calibration
Multiwavelength UV-Vis detector	Determination of structural geometry variation in co-polymers
Multiangle light scattering detector (MALLS) SLD7100	Determination of absolute molecular weight, applicable starting at 10.000 g/mol, used for peptides, natural polymers, etc.
Viscometer detector DVD 1260	Determination of molecular weight by viscosity, applicable starting at 5.000 g/mol

Fast protein liquid chromatography (FPLC)

Purification of (recombinant) proteins from cell lysates.

system	short description
Column	Various column materials for protein purification
UV-Detector (UV-900)	Detection of proteins
Conductivity detector and pH-detector (P/C-900)	Monitoring of conductivity and pH value

2.3. Other methods

Autotitrator

system	short description
Applications	Saponification value (DIN 53401)Saponification value lignin Modification Acid value (DIN 53402) OH-value (DIN 53240) End group determination of Polymers Acid-base titration Karl-Fischer-titration

TOC Analyzer

The TOC analyzer is used to determine the environmental parameters of TOC, NPOC, TC, TIC and POC in aqueous samples. The TN add-on module can also be used to determine TN_b.

system	short description
Digestion method	High-temperature combustion up to 950 °C
TN Detector	Electrochemical „solid-state“ detector
Measurable parameters	TC, TIC, TOC, NPOC, NPOCplus, POC, TN
Measurement range (detection limit)	0 – 30.000 mg/L C (4 µg/L C) 0 – 100 mg/L TN_b (0,05 mg/L TN_b)
Sample supply	Automatic flow injection with automatic acidification/blowing out of the samples, rinsing technology and dilution option

3. Material characterization

3.1. Thermal analysis

Differential scanning calorimetry (DSC)

Measurement of heat flow variations occurring due to temperature- or time-dependent changes of the physical or chemical sample properties (phase transitions).

system	short description
Temperature	-80 °C – 500 °C
Gases	N₂, air
Heating rate	0,02 – 300 K/min
Cooling rate	0,02 – 50 K/min

Thermogravimetric analysis (TGA)

Measurement of mass changes of a sample depending on heat and time.

system	short description
Temperature	Up to 1100 °C
Heating rate	0,02 – 150 K/min
Sample volume	Up to 900 µL

Sorption unit
Temperature	Up to 95 °C
Rel. humidity	100 %

Determination of the heat deflection temperature (HDT) (not yet in use)

The HDT/Vicat is used to determine the heat deflection temperature, the softening temperature and the creep behavior of various polymers.

system	short description
Temperature	Up to 300 °C
Testing according to	DIN EN ISO 75 1-3, DIN EN ISO 306
Monitoring stations	4
Evaluation of results	Statistical evaluation and presentation as a results table, figure and test report.

3.2. Mechanical properties

Pendulum impact tester

The pendulum impact tester is used to determine the impact strength of various polymers.

SYSTEM	SHORT DESCRIPTION
Working capacity	Up to 50 J
Testing according to	DIN EN ISO 179 (Charpy), DIN EN ISO 180 (Izod)
3 pendumlums each	0.5 J, 2 J und 5 J (Charpy); 1 J, 2.75 J and 5.5 J (Izod)
Evaluation of results	Statistical evaluation and presentation as a results table, figure and test report.

Universal testing machine

For determining the mechanical properties of various polymers.

SYSTEM	SHORT DESCRIPTION
Testing options	Tensile test according to DIN EN ISO 527 1-3, 3-point flexure tests according to DIN EN ISO 178
Test force range	Up to 20 kN
Force transducer	2,5 kN
Strain transducer	Video extensometer (optical)
Sample holder	Pneumatic with adjustable closing pressure, test force 2.5 kN
Evaluation of results	Statistical evaluation and presentation as a results table, figure and test report.

Shore hardness (DIN ISO 7619-1)

Digital shore hardness type A and type D with test bench.

system	short description
Typ A	For soft materials
Typ D	For medium to hard materials
Resolution	0,1
Accuracy	≤ 1 %

Rheology/DMA (coming 2025)

Establishment of a high-performing combination device for shear-reological investigations under rotation and oszillation and dynamic-mechanical analysis of solids under bending, tension and compression.

Capillary viscometry by Ubbelohde-viscosimeter

Determination of the reduced intrinsic viscosity of diluted solutions of soluble polymers.

system	short description
Testing according to	DIN EN ISO 307, DIN EN ISO 1628 etc.
Solvents	m-cresol Sulfuric acid Formic acid
Viscosimeter	Ubbelohde and micro-Ubbelohde (DIN 51562)

system

short description

Testing according to

DIN EN ISO 307, DIN EN ISO 1628 etc.

Solvents

m-cresol

Sulfuric acid

Formic acid

Viscosimeter

Ubbelohde and micro-Ubbelohde (DIN 51562)

3.3. Other methods

Microscopy

For reflected- and transmitted light applications.

system	short description
Lenses	Fiber analysis: 5x, 10x, 20x, 50x Microbiology: 40x, 100x (Ölimmersion)
5 Mp camera	High-resolution camera for optimal imaging
Test bench with 3-axes motorization	Software-automatized imaging with high depth of field
Brightfield / darkfield polarization Phase contrast Ph1/Ph2/Ph3 Transmitted light Polarization with additional Lambda-plate	Multitude of contrast-/polarization options for reflected- and transmitted light applications for optimal structure imaging

Density measurement of solids and fluids

Solids: Density balance DIN EN ISO 1183.

Fluids: Density meter (flexural resonator) for measurements of viscous samples according to DIN EN ISO 5725 with adapter heating.

system	short description
Density range	0 g/cm³ – 3 g/cm³
Temperature range	0 °C – 100 °C
Sample volume	Ca. 1 mL
Accuracy	0,0001 g/cm³

Conditioning of specimen

Climatic chamber for constant conditions for the storage of specimen under standard atmosphere at 23 °C and 50 % relative humidity.

publications

Download brochures and product sheets

Brochure “Laboratory for technical biopolymers”

Download

Product sheet “The miniplant of the laboratory for technical biopolymers”

Download

Brochure “BioCat – Combination of biotechnological and chemical processes”

Download

Scientific publications

Jahr Year	Titel/Autor:in Title/Author	Publikationstyp Publication Type
2024	A green process for the specific decomposition of chicken feather keratin into polythiol building blocks Schieder, Andreas; Diener, Julia; Diekmann, Martin; Bartsch, Christian; Dietrich, Florian; Falcke, Claudia; Anic, Iva; Roth, Steffen; Sieber, Volker; Richter, Michael; Taden, Andreas	Zeitschriftenaufsatz Journal Article
2024	Syntheses and polymerization of monoterpene-based (meth)acrylates: IBO(M)A as a relevant monomer for industrial applications Obermeier, Franziska; Hense, Dominik; Stockmann, Paul; Strube, Oliver Ingolf	Zeitschriftenaufsatz Journal Article
2023	Chicken feather keratin - a valuable source for polythiol building blocks Schieder, Andreas; Diener, Julia; Diekmann, Martin; Bartsch, Christian; Dietrich, Florian; Falcke, Claudia; Anic, Iva; Roth, Steffen; Sieber, Volker; Taden, Andreas; Richter, Michael	Poster
2023	ATP production from electricity with a new-to-nature electrobiological module Luo, Shanshan; Adam, David; Giaveri, Simone; Barthel, Sebastian; Cestellos-Blanco, Stefano; Hege, Dominik; Paczia, Nicole; Castaneda Losada, Leonardo; Klose, Melanie; Arndt, Fabian; Heider, Johann; Erb, Tobias J.	Zeitschriftenaufsatz Journal Article
2023	In situ H2O2 Generation by Choline Oxidase and Its Application in Amino Polysaccharide Degradation by Coupling to Lytic Polysaccharide Monooxygenase Hoang, Nam-Hai; Golten, Ole; Forsberg, Zarah; Eijsink, Vincent G.H.; Richter, Michael	Zeitschriftenaufsatz Journal Article
2023	Deutsche Normungsroadmap Circular Economy	Bericht Report
2022	A High-Throughput Continuous Spectroscopic Assay to Measure the Activity of Natural Product Methyltransferases Simon-Baram, H.; Roth, Steffen; Niedermayer, Christina; Huber, Patricia; Speck, Melanie; Diener, Julia; Richter, Michael; Bershtein, S.	Zeitschriftenaufsatz Journal Article
2022	(+)-Limonene-Lactam: Synthesis of a Sustainable Monomer for Ring-Opening Polymerization to Novel, Biobased Polyamides Kleybolte, M.M.; Zainer, Laura; Liu, J.Y.; Stockmann, Paul; Winnacker, M.	Zeitschriftenaufsatz Journal Article
2021	Enhanced C2 and C3 Product Selectivity in Electrochemical CO2 Reduction on Carbon-Doped Copper Oxide Catalysts Prepared by Deep Eutectic Solvent Calcination Iwanow, Melanie; Seidler, Johannes; Vieira, Luciana; Kaiser, Manuela; Opdenbosch, Daniel Van; Zollfrank, Cordt; Gärtner, Tobias; Richter, Michael; König, Burkhard; Sieber, Volker	Zeitschriftenaufsatz Journal Article
2021	Bioelectrocatalytic cofactor regeneration coupled to CO2 fixation in a redox-active hydrogel for stereoselective C-C bond formation Castañeda-Losada, Leonardo; Adam, David; Paczia, Nicole; Buesen, Darren; Steffler, Fabian; Sieber, Volker; Erb, Tobias; Richter, Michael; Plumeré, Nicolas	Zeitschriftenaufsatz Journal Article
2021	Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids Subrizi, F.; Wang, Y.; Thair, B.; Méndez-Sánchez, D.; Roddan, R.; Cárdenas-Fernández, M.; Siegrist, J.; Richter, M.; Andexer, J.N.; Ward, J.M.; Hailes, H.C.	Zeitschriftenaufsatz Journal Article
2021	Sustainable chemistry - An interdisciplinary matrix approach Richter, Michael; Vieira, Luciana; Sieber, Volker	Zeitschriftenaufsatz Journal Article
2020	Activated carbon as catalyst support: Precursors, preparation, modification and characterization Iwanow, M.; Gärtner, Tobias; Sieber, V.; König, B.	Zeitschriftenaufsatz Journal Article
2020	Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases Roddan, R.; Sula, A.; Méndez-Sánchez, D.; Subrizi, F.; Lichman, B.R.; Broomfield, J.; Richter, M.; Andexer, J.N.; Ward, J.M.; Keep, N.H.; Hailes, H.C.	Zeitschriftenaufsatz Journal Article
2020	Biobased chiral semi-crystalline or amorphous high-performance polyamides and their scalable stereoselective synthesis Stockmann, P.N.; Opdenbosch, D. van; Poethig, A.; Pastoetter, D.L.; Hoehenberger, M.; Lessig, S.; Raab, J.; Woelbing, M.; Falcke, C.; Winnacker, M.; Zollfrank, C.; Strittmatter, H.; Sieber, V.	Zeitschriftenaufsatz Journal Article
2020	Pyrolysis of Deep Eutectic Solvents for the Preparation of Supported Copper Electrocatalysts Iwanow, M.; Vieira, L.; Rud, I.; Seidler, J.; Kaiser, M.; Opdenbosch, D. Van; Zollfrank, C.; Richter, M.; Gärtner, Tobias; König, B.; Sieber, V.	Zeitschriftenaufsatz Journal Article
2019	New bio-polyamides from terpenes: a-pinene and (+)-3-carene as valuable resources for lactam production Stockmann, Paul; Pastötter, Dominik L.; Wölbing, Marion; Falcke, Claudia; Winnacker, Malte; Strittmatter, Harald; Sieber, Volker	Zeitschriftenaufsatz Journal Article
2019	Isomeren-angereicherte 3-Caranlactame und darauf basierende Polyamide mit hoher optischer Reinheit und einstellbarer Kristallinität für Hochleistungsanwendungen Falcke, Claudia; Sieber, Volker; Stockmann, Paul; Strittmatter, Harald	Patent
2019	Verfahren zur Herstellung eines verklebte Elemente aufweisenden Erzeugnisses Falcke, Claudia; Faltl, Christina; Diener, Julia; Richter, Michael; Sieber, Volker; Landen, Franz Josef	Patent
2018	Chemo-enzymatische Synthese eines neuartigen Borneol-basierten Polyesters Roth, Steffen; Hofer, Michael; Sieber, Volker	Zeitschriftenaufsatz Journal Article
2018	Enzymatic synthesis of lignin-based concrete dispersing agents Jankowska, D.; Heck, T.; Schubert, M.; Yerlikaya, A.; Weymuth, C.; Rentsch, D.; Schober, I.; Richter, M.	Zeitschriftenaufsatz Journal Article
2018	Structural and mutagenesis studies of the thiamine-dependent, ketone-accepting YerE from Pseudomonas protegens Hampel, Sabrina; Steitz, Jan-Patrick; Baierl, Anna; Lehwald, Patrizia; Wiesli, Luzia; Richter, Michael; Fries, Alexander; Pohl, Martina; Schneider, Gunter; Dobritzsch, Doreen; Müller, Michael	Zeitschriftenaufsatz Journal Article
2017	Preparation of supported palladium catalysts using deep eutectic solvents Iwanow, M.; Finkelmeyer, J.; Söldner, A.; Kaiser, M.; Gärtner, Tobias; Sieber, V.; König, B.	Zeitschriftenaufsatz Journal Article
2017	Chemoenzymatic synthesis of a novel borneol-based polyester Roth, S.; Funk, I.; Hofer, M.; Sieber, V.	Zeitschriftenaufsatz Journal Article
2017	Catalytic alkylation using a cyclic S-adenosylmethionine regeneration system Mordhorst, Silja; Siegrist, Jutta; Müller, Michael; Richter, Michael; Andexer, Jennifer N.	Zeitschriftenaufsatz Journal Article
2017	Functional and structural characterisation of a bacterial O-methyltransferase and factors determining regioselectivity Siegrist, J.; Netzer, J.; Mordhorst, S.; Karst, L.; Gerhardt, S.; Einsle, O.; Richter, M.; Andexer, J.N.	Zeitschriftenaufsatz Journal Article
2017	Catalytic alkylation using a cyclic S-adenosylmethionine regeneration system Mordhorst, Silja; Siegrist, Jutta; Müller, Michael; Richter, Michael; Andexer, Jennifer N.	Zeitschriftenaufsatz Journal Article
2016	A FRET-based biosensor for the detection of neutrophil elastase Schulenburg, C.; Faccio, Greta; Jankowska, D.; Maniura-Weber, K.; Richter, Michael	Zeitschriftenaufsatz Journal Article
2016	Auf Terpentlactam basierende Polyamide Falcke, Claudia; Strittmatter, Harald; Wölbing, Marion; Sieber, Volker	Patent
2016	Back Cover: Preparation of Magnesium, Cobalt and Nickel Ferrite Nanoparticles from Metal Oxides using Deep Eutectic Solvents (Chem. Eur. J. 37/2016) Söldner, A.; Zach, J.; Iwanow, M.; Gärtner, Tobias; Schlosser, M.; Pfitzner, A.; König, B.	Zeitschriftenaufsatz Journal Article
2016	Fermentative Produktion terpenbasierter Monomere für Biopolymere Roth, Steffen; Hofer, Michael; Sieber, Volker	Zeitschriftenaufsatz Journal Article
2016	Preparation of magnesium, cobalt and nickel ferrite nanoparticles from metal oxides using deep eutectic solvents Söldner, Anika; Zach, Julia; Iwanow, Melanie; Gärtner, Tobias; Schlosser, Marc; Pfitzner, Arno; König, Burkhard	Zeitschriftenaufsatz Journal Article
2015	Regiocomplementary O-methylation of catechols by using three-enzyme cascades Siegrist, Jutta; Aschwanden, Simon; Mordhorst, Silja; Thöny-Meyer, Linda; Richter, Michael; Andexer, Jennifer N.	Zeitschriftenaufsatz Journal Article
2014	Chemo-enzymatische Synthese bifunktioneller Campherderivate Hofer, Michael; Strittmatter, Harald; Sieber, Volker	Zeitschriftenaufsatz Journal Article
2013	Enzymatic cleavage of lignin beta-O-4 aryl ether bonds via net internal hydrogen transfer Reiter, J.; Strittmatter, H.; Wiemann, Lars O.; Schieder, D.; Sieber, V.	Zeitschriftenaufsatz Journal Article
2013	Biocatalytic synthesis of a diketobornane as a building block for bifunctional camphor derivatives Hofer, M.; Strittmatter, H.; Sieber, V.	Zeitschriftenaufsatz Journal Article

Diese Liste ist ein Auszug aus der Publikationsplattform Fraunhofer-Publica

This list has been generated from the publication platform Fraunhofer-Publica

projects

AquaCat

Dr. Pranee Inprakhon, lecturer of Mahidol University, Bangkok Thailand, has been awarded a Marie Curie International Incoming Fellowship (IIF) from the European Union.

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Bi-Amin

The aim of the project team is to develop such enzymatic reaction routes for the biosynthesis of amines and to scale up this process to the pilot scale.

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BioAcrylate

The aim of the part of the project worked on at Fraunhofer was the optimization of the synthesis of bio-based acrylic acid from activated lactic acid derivatives.

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BioDiMet

The aim of the BioDiMet project is the development of a robust and straightforward biocatalytic methyltransferase toolbox that can be applied for the selective synthesis of novel bioactives or precursors in an industrial setting.

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BioFraMe II

BioFraMe is an innovative, broadly applicable supporting material for the preparation of bio‑based heterogeneous metal catalysts.

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BioSurf

We aim at an increased replacement of petro-based surfactants by biosurfactants generated form renewable resources.

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ChiBio

ChiBio is adopting the approach of a biorefinery in order to use the biogenic waste material in a holistic way, in other words materially and energetically and as efficiently and completely as possible.

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ChitoLogEn

ChitoLogEn is an innovative chitosan-based redox-active polymer. It works as a biobased matrix for the immobilization of redox enzymes on electrodes with applications in bioelectrocatalytic processes including bioelectrosynthesis and energy conversion.

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ChitoMat

Holistic Chitin conversion to materials for 3D printing application and performance animal feed additives.

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eBioCO₂n

The project pursues an ambitious approach to converting CO₂ into chemicals with electricity from renewable sources: Similar to photosynthesis, CO₂ is to be fixed with electron-transmitting biocatalysts and then linked to further enzymatic conversion steps.

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November 2023 – October 2026

ECOMO

Electrobiocatalytic cascade for bulk reduction of CO₂ to CO coupled to fermentative production of high value diamine monomers

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January 2024 – December 2026

eCO₂DIS

Simulation-guided development of an electricity or H₂-driven in-vitro acetyl-CoA production module as platform chemical from CO₂ for diversity oriented synthesis

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HanAkku

HanAkku are innovative and easy-to-manufacture 100 percent bio-based hemp shive materials for the targeted storage of substances from solutions and their release (biodepots) for diverse use in the energy, water and agricultural sectors.

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Hydrophobic proteins for surface functionalization

Binding of functional proteins to membrane surfaces can provide them with new properties.

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KERAbond

Plastics and specialty chemicals made from the biopolymer raw material keratin (the main component of animal feathers) to replace fossil sources.

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Laboratory for Technical Biopolymers

The Laboratory for Technical Biopolymers is a project to support companies, especially SMEs, on their way to innovative and sustainable substances and materials as well as to resource-efficient processes.

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Liberate

Goal of the project Liberate is the electrochemical cleavage of lignin for the production of phenol derivatives suitable to replace fossil resources.

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Lignoplast

Developed processes for the chemical industry to produce plastics from wood. The basis are lignins contained in woody biomass.

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LiMeOx

In the LiMeOx project tailor-made biobased plasticizers are produced from monoterpenes.

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PFIFF

The aim of the part of the project worked on at Fraunhofer was the development of a procedure for the purification of Furandicarboxylic acid (FDCA).

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PFIFFIG

The aim of the PFIFFIG follow-up project is to further develop the manufacturing process targeting industrial grade.

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ShaPID

In the lighthouse project, technology developments are being driven forward in four complementary areas to demonstrate that sustainable, green chemistry can be achieved through process intensification and digitalization.

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Tape2Grape

Tape2Grape is a 100 percent bio-based multifunctional grafting tape for fruit and ornamental trees, which can be equipped with individual biological ingredients.

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TerPa

This project aims to demonstrate a possible solution en route to a biobased economy, as expected by the German Sustainability Strategy or the National Research Strategy Bioeconomy 2030.

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Xylophon

Lubricants used in the manufacturing industry are still mainly produced petrochemically from fossil resources.

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Further projects

BiOptik

DiMeFu (more info only in German)

MapLup

TAKEMA

Tabbed contents

Our research

Sustainable syntheses and materials

Fields of activity and technologies

Bioinspired synthesis routes

Organic chemistry

Bioorganic chemistry

Biobased polymers and materials

Biobased polymers and additives

Plastics technology

Biohybrid materials

Laboratory for technical biopolymers ‒ LTBP

Terpene-based polyamides: Caramid-R® and Caramid-S®

Range of services

Research and Development

Cooperation for research projects

Characterization

We also offer services concerning materials and (biobased) polymers as part of the Laboratory for Technical Biopolymers (LTBP):

equipment

Synthesis/processing

Analytics

Material characterization

1. Synthesis/processing

2. Analytics

2.1. Chemical structure determination

2.2. Chromatographic methods

2.3. Other methods

3. Material characterization

3.1. Thermal analysis

3.2. Mechanical properties

3.3. Other methods

publications

Download brochures and product sheets

Brochure “Laboratory for technical biopolymers”

Product sheet “The miniplant of the laboratory for technical biopolymers”

Brochure “BioCat – Combination of biotechnological and chemical processes”

Scientific publications

Related Links:

projects

AquaCat

Bi-Amin

BioAcrylate

BioDiMet

BioFraMe II

BioSurf

ChiBio

ChitoLogEn

ChitoMat

eBioCO2n

ECOMO

eCO2DIS

HanAkku

Hydrophobic proteins for surface functionalization

KERAbond

Laboratory for Technical Biopolymers

Liberate

Lignoplast

LiMeOx

PFIFF

PFIFFIG

ShaPID

Tape2Grape

TerPa

Xylophon

Further projects

Terpene-based polyamides: Caramid-R^® and Caramid-S^®

eBioCO₂n

eCO₂DIS