iP-OSTEO – Induced pluripotent stem cell seeded active osteochondral nanofibrous scaffolds

In February 2019, the MSCA‑RISE project iP‑Osteo commenced work with the participation of Fraunhofer IGB and will reach its goals by creating an international and interdisciplinary training program. Seven companies (SMEs) and seven academic institutions across the European Union will join their forces through dedicated secondments. The activities will involve networking, research, training, workshop and dissemination secondments. The project has in total 239 secondments involving exchange of early‑stage and experienced researchers. The consortium is bonded by Dr. Eva Filova, a young scientist with experience in bone and cartilage tissue engineering.

A total of 14 institutions from ten European countries are conducting research on this novel technology, which combines iPSCs with improved regeneration capacity and nanostructured scaffolds based on electrospun scaffolds as well as a drug delivery system stimulating cell regeneration based on electrosprayed and spray‑dried particles. The system will deliver a novel treatment method for older patients, for which the current cellular and cell‑free methods are ineffective.

The project has 169 ESR secondment months leading to training of new generation of scientists with international connection and knowledge of intrasectorial environment, who will help diseased people by providing novel therapeutic methods.